All times listed are Central Daylight Time. Program and Faculty are updated often – check back for the most up-to-date information. Click on session name to view session description and component talks.
0599: Efficacy of Statin Medications for Secondary Prevention of Atherosclerotic Cardiovascular Disease Among Patients with Systemic Lupus Erythematosus
Location: Hall F1
Abstract Poster Presenter: Aakash Patel, MD – Massachusetts General Hospital
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0600: Toward a Consensus-Based Definition of Difficult-to-Treat Systemic Lupus Erythematosus: A Multinational Survey of Clinicians from the MENA Region
0601: Precipitants and Long-Term Outcomes of Posterior Reversible Encephalopathy Syndrome in Systemic Lupus Erythematosus: A Multicenter Cohort Study and Systematic Review
0602: Association of Systemic Lupus Erythematosus with Healthcare Resource Utilization and Healthcare Expenditures: Analysis of Nationally Representative Data, 2017-2022
Location: Hall F1
Abstract Poster Presenter: Ami Vyas, PhD – University of Rhode Island
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0603: Transverse Myelitis in Systemic Lupus Erythematosus: Disease Manifestations and Clinical Outcomes from Multi-Center Data
Location: Hall F1
Abstract Poster Presenter: Amir Daneshvar, MD – University Hospitals Cleveland Medical Center/Case Western Reserve University
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0604: Assessment of the Metabolic Score for Insulin Resistance (METS-IR) and Its Associated Factors in Patients with Systemic Lupus Erythematosus
0605: The Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) Predicts Worsening Self-Efficacy in the Patients from the Almenara Lupus Cohort
0611: Venous Thromboembolism in Patients with Lupus Nephritis: Frequency and Risk Factors – A Cohort Study
Location: Hall F1
Abstract Poster Presenter: Fadi Kharouf, MD – Hadassah Medical Center - Toronto Western Hospital
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0612: Is Antimalarial Use Associated with a Reduced Risk of Lupus Nephritis in Patients with SLE? Results from an Inception Cohort-Based Study
Location: Hall F1
Abstract Poster Presenter: Fadi Kharouf, MD – Hadassah Medical Center - Toronto Western Hospital
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0614: Evaluating Cardiovascular Risk in Systemic Lupus Erythematosus: Comparing Novel Risk Scores with Carotid Ultrasound
Location: Hall F1
Abstract Poster Presenter: Ileana Cecilia Reynosa Silva, MD – Universidad Autonoma de Nuevo Leon, Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0615: Systemic Lupus Erythematosus Flares in Patients with End-Stage Kidney Disease on Renal Replacement Therapy or after Transplant
Location: Hall F1
Abstract Poster Presenter: Jacob Klein, MD – Ohio State University Wexner Medical Center
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0618: Therapeutic landscape of systemic lupus erythematosus pure membranous nephropathy: a nationwide population-based study
Location: Hall F1
Abstract Poster Presenter: Kevin Chevalier – Université Paris Cité
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0619: Interim Analysis of the Impact of a Recombinant Herpes Zoster Vaccine on Systemic Lupus Erythematosus: A Randomized Controlled Study on Immunogenicity, Safety and Immunosuppressor Effects
Location: Hall F1
Abstract Poster Presenter: Luciana Seguro, MD, PhD – Hospital das Clínicas HCFMUSP, University of Sao Paulo
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0620: The usefulness of neutrophil-to-lymphocyte ratio as a biomarker to predict lupus flares in patients under remission
0622: Shrinking Lung Syndrome in Systemic Lupus Erythematosus: A Pooled Database Analysis of Clinical, Immunological and Therapeutic Factors Impacting Outcomes
0623: Cluster Analysis of Socioeconomic and Environmental Determinants Modifying Activity, Chronicity and Clinical Manifestations of Systemic Lupus Erythematosus in the GLADEL 2.0 Cohort
0625: DNA methylation patterns in systemic lupus erythematosus associated with nephritis status
Location: Hall F1
Abstract Poster Presenter: Meghan Nelson, DO – National Institutes of Health
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0626: Evaluation of Novel Anti-ATP1A1 Autoantibodies by ELISA to Predict Cardiac Neonatal Lupus (Cardiac-NL)
Location: Hall F1
Abstract Poster Presenter: Nalani Sachan, PhD – NYU Grossman School of Medicine
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0627: Marked Decline in SLE Mortality Despite Rising Mortality in the General Population During the COVID-19 Pandemic
Location: Hall F1
Abstract Poster Presenter: Omer Pamuk, MD – University Hospitals Cleveland Medical Center/ Case Western Reserve University
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0628: Α user-friendly machine-learning tool for early damage prediction in patients with Systemic Lupus Erythematosus
Location: Hall F1
Abstract Poster Presenter: Panagiotis Garantziotis, MD – Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0630: Development, Validation and Performance of a Patient Knowledge Assessment Tool for Assessing the Immediate and Short-term Impact of an Information Course in Systemic Lupus Erythematosus
0632: Comparative Outcomes of GLP-1 Receptor Agonists Versus SGLT2 Inhibitors in Patients with Systemic Lupus Erythematosus and Diabetes: A Propensity-Matched Retrospective Cohort Study
0634: Association of Lifestyle and Integrative Health Practices with Health-related Quality of Life in Women with Systemic Lupus Erythematosus and Connective Tissue Disease
0640: Impact of Clinically Important Improvements in Patient-Reported Outcomes on Disease Activity in Patients With Systemic Lupus Erythematosus Treated With Upadacitinib or Placebo: Results From the Phase 2 SLEek Study
0642: Belimumab-Based Triple Therapy in Proliferative Lupus Nephritis: Renal Outcomes and Glucocorticoid Tapering in a Real-World Multicenter Cohort
Location: Hall F1
Abstract Poster Presenter: Javier Narvaez, PhD – Hospital Universitario de Bellvitge
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0644: Improvement of Fatigue, Musculoskeletal Pain, and Morning Stiffness in Patients with Systemic Lupus Erythematosus Treated with Dapirolizumab Pegol: 48-Week Results from a Phase 3 Trial
Location: Hall F1
Abstract Poster Presenter: Joan Merrill, MD – Oklahoma Medical Research Foundation
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0645: Achievement of Low Disease Activity and Remission in Patients with Systemic Lupus Erythematosus Treated with Dapirolizumab Pegol: 48-week Results from a Phase 3 Trial
0649: Belimumab Real-World Effectiveness in Chinese Patients with Systemic Lupus Erythematosus: Interim Analysis of an Ambidirectional, Observational Cohort Study (RELIABLE)
0650: Obinutuzumab Demonstrates Steroid-Sparing Effects and Consistent Benefit In Patients with Lupus Nephritis When Using Multiple Primary Endpoint Definitions: A Secondary Analysis of Phase III Trial Results
Location: Hall F1
Abstract Poster Presenter: Brad Rovin, MD – The Ohio State University
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0651: The ERβ Agonist, OSU-ERβ-012, Suppresses Systemic, Kidney and Heart Inflammation in a Chimeric Mouse Model of Systemic Lupus Erythematosus
Location: Hall F1
Abstract Poster Presenter: Braden Zeno, BS – Ohio State University
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0652: Evolution and Readiness: Preparing for Cell Therapy in Lupus Trials, A LuCIN Network Evaluation
0653: In Vitro Pharmacological Profile of GLPG3667 Suggests Differentiation from the TYK2 Inhibitors Deucravacitinib and Zasocitinib at Their Clinical Dose Regimens
0654: Obinutuzumab Shows Promise in Lupus Nephritis Regardless of Baseline Serological Markers: An Exploratory Post Hoc Analysis of a Phase II Trial
Location: Hall F1
Abstract Poster Presenter: Ed Vital, MD – University of Leeds
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0655: Blood pressure remains elevated in patients initiating voclosporin with low baseline blood pressure: evidence from patients in routine clinical care
Location: Hall F1
Abstract Poster Presenter: Eric Roberts, PhD, MPH – University of California, San Francisco
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0656: Low-dose belimumab reduced disease flares in patients with systemic lupus erythematosus at low disease activity: a multicenter, randomized, double-blind, placebo-controlled trial
0657: Preliminary Analysis Of Open-Label Dose-Titration Phase Of SLE Treatment With N-Acetylcysteine (SNAC) Shows Evidence For Potential Improvement Of SLEDAI, BILAG, ADHD And Fatigue Scores In Patients With Active SLE
Location: Hall F1
Abstract Poster Presenter: FNU Ruchi, MD – SUNY Upstate Medical University
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0659: Human papillomavirus infection and systemic lupus erythematosus under biologic therapy: a retrospective analysis in a multicenter cohort
0660: Effects of Deucravacitinib on Dysregulated Autoimmune Gene Modules That Correlate With Skin Disease Severity and Treatment Response in Patients With Cutaneous Manifestations of Lupus Erythematosus: Biomarker Results From a Global, Randomized, Placebo-Controlled Phase 2 Study
0662: Efficacy Across Baseline Characteristic Subgroups in Patients With Systemic Lupus Erythematosus Treated With Upadacitinib: Results From SLEek, a Phase 2 Randomized
0664: Pharmacodynamic Effects of Obinutuzumab on B cells and Serological Markers in Patients With Active Lupus Nephritis: Results From a Phase III Trial
0665: Infusion-Related Reactions (IRRs) and Hematologic Events Associated With Obinutuzumab in Lupus Nephritis: A Secondary Analysis of a Phase III Trial
0666: Reported Adverse Events Associated With Systemic Lupus Erythematosus (SLE) Treatment: Insights From the FDA Adverse Event Reporting System (FAERS) 2023
0669: Clinical and Laboratory Factors Associated With Biopsy-Confirmed Antimalarial-Induced Cardiomyopathy
Location: Hall F1
Abstract Poster Presenter: Youngmin Kim, MD – Brigham and Women's Hospital
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0670: Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extra-renal Systemic Lupus Erythematosus – A Systematic Review & Meta-analysis
0613: A Baseline Kidney Biopsy Is Not Always Feasible in Incident Lupus Nephritis: Insights from an Inception Cohort
Location: Hall F1
Abstract Poster Presenter: Fadi Kharouf, MD – Hadassah Medical Center - Toronto Western Hospital
Sunday, Oct 26th
10:30 AM - 12:30 PM Central Time
0616: Neurofilament Light Chain Serum Levels is Associated with Neuropsychiatric Manifestations and Cognitive Dysfunction in Systemic Lupus Erythematosus Patients: A Longitudinal Study
0631: Antibodies to Type I and Type III Interferons at Diagnosis Predispose to Serious Infections on Follow up in an Inception Cohort of SLE (INSPIRE) from India
0617: Autoantibodies to Extracellular Antigens in Lupus Patients Serum Versus Controls; Predominance of Autoantibodies to Type I Interferons in Lupus Sera
0801: Achieving Sustained Lupus Low Disease Activity State and Remission with Ianalumab (VAY736) in Patients with Systemic Lupus Erythematosus: A Post Hoc Analysis from a Phase II Study
Location: S103
Presenting Author: Ed Vital, MD – University of Leeds
Sunday, Oct 26th
1:15 PM - 1:30 PM Central Time
0802: Remission from cutaneous manifestations of lupus with enpatoran, a first-in-class oral small molecule toll-like receptor 7/8 inhibitor: pooled post-hoc exploratory analysis from a randomized placebo-controlled Phase II study
0803: Improved Efficacy and Safety Outcomes in Patients with SLE Treated with Belimumab (BEL) Versus Immunosuppressants (IS), in Addition to Antimalarials (AM) and Glucocorticoids (GC): A Post Hoc Summary of Five Phase 3 Trials
0806: Comparative Risk of Infection-Related Complications in Systemic Lupus Erythematosus Patients Treated with Anifrolumab versus Belimumab: A Target Trial Emulation
0838: Complete Renal Response and Long-Term, Progression-Free Survival in Adult Patients With Lupus Nephritis: A Retrospective Cohort Study in the United States
Location: S102
Presenting Author: Brad Rovin, MD – The Ohio State University
Sunday, Oct 26th
3:30 PM - 3:45 PM Central Time
0839: Precision Liquid Biopsy for Lupus Nephritis: cfDNA Methylation and Fragmentomic Signatures Enable Non-Invasive Diagnosis and Dynamic Disease Tracking
Location: S102
Presenting Author: Iris Tang, MBBS, MRCP – Department of Medicine, LKS Faculty of Medicine, University of Hong Kong
Sunday, Oct 26th
3:45 PM - 4:00 PM Central Time
0840: Shared and Distinct Urinary Proteomic Signatures of Lupus Nephritis and Other Glomerular Diseases
Location: S102
Presenting Author: Andrea Fava, MD – Johns Hopkins University
Sunday, Oct 26th
4:00 PM - 4:15 PM Central Time
0841: Comparing the Impact of GLP-1 Agonists and SGLT-2 Inhibitors on Outcomes in Lupus Nephritis: A Retrospective Cohort Study
Location: S102
Presenting Author: Kinga Grzybowski, MD – Jefferson Einstein Montgomery Hospital
Sunday, Oct 26th
4:15 PM - 4:30 PM Central Time
0842: Association of Urinary Biomarkers with Histological Features in Diagnostic and Per-protocol Repeat Kidney Biopsies in Lupus Nephritis
Location: S102
Presenting Author: Andrea Fava, MD – Johns Hopkins University
Monday, Oct 27th
10:30 AM - 11:30 AM Central Time
27M31: Rheumatology Research Foundation Memorial Lecture: To Memoralize Dr. Eng Tan
1469: Remission, Low Level Disease Activity State (LLDAS) and Relapse in Patients With Early-Onset, Adult-Onset and Late-Onset Systemic Lupus Erythematosus
1477: Can Large Language Models Support Clinical Decision-Making in Atypical SLE? A Comparative Analysis
Location: Hall F1
Abstract Poster Presenter: Beste Acar, MD – Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1478: Construction and Validation of a Prediction Model of Cognitive Dysfunction in Patients with Systemic Lupus Erythematosus
Location: Hall F1
Abstract Poster Presenter: Bin zhou, MD – The First School of Clinical Medicine, Southern Medical University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1479: Validation of Attention, Memory, and Frontal-Executive Abilities Screening Test (AMFAST) in Systemic Lupus Erythematosus (SLE), a prospective single-center study in The Bronx
Location: Hall F1
Abstract Poster Presenter: Chen Chao, MD, MBA – Montefiore Medical Center/Albert Einstein College of Medicine
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1480: Urinary Biomarkers Detect Proliferative Lupus Nephritis in SLE Patients with Subclinical Proteinuria.
Location: Hall F1
Abstract Poster Presenter: Chen-Yu Lee, MD – Johns Hopkins University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1481: Duffy Antigen Screening in Systemic Lupus Erythematosus Patients with Neutropenia: A Quality Improvement Initiative
1482: Evaluation of T Cell Subpopulations, CD4/CD8 Ratio and p16INK4a in Patients with Systemic Lupus Erythematosus and Cognitive Impairment
Location: Hall F1
Abstract Poster Presenter: Erik Cimé-Aké, n/a – Instituto Nacional de Ciencias Médicas y Nutrición. Salvador Zubirán. Immunology and Rheumatology Department
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1483: Evidence of Early Cardiovascular Dysfunction in Young Systemic Lupus Erythematosus Patients Compared to Older Healthy Controls
1486: Systemic Lupus Erythematosus and Statins in GLADEL 2.0: Are Cardiovascular Risk Prevention Guidelines Being Followed?
Location: Hall F1
Abstract Poster Presenter: Ileana Cecilia Reynosa Silva, MD – Universidad Autonoma de Nuevo Leon, Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1487: Whole Health Empowerment for Endotypes of Lupus (WHEEL) Program: User Testing Findings on Feasibility, Acceptability, and Opportunities for Intervention Refinement
1493: Long-Term Outcomes in Systemic Lupus Erythematosus Patients Infected with SARS-CoV-2: Variant-Specific Analysis of Pre-Delta/Delta and Omicron Periods
1496: Demyelinating Syndromes in Systemic Lupus Erythematosus: A 23-Year Retrospective Analysis of Clinical Features and Treatment Outcomes from a Tertiary Care Center
Location: Hall F1
Abstract Poster Presenter: Manikandan Gopal, DM – Christian Medical College Vellore
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1497: Acute Care Utilization in Patients with Antiphospholipid Syndrome And/or Systemic Lupus Erythematosus
1500: Prognostic Impact of Thrombocytopenia on Morbidity and Mortality in Systemic Lupus Erythematosus: A Retrospective Single-Center Study
Location: Hall F1
Abstract Poster Presenter: Milad Heydari-Kamjani, DO – University Hospitals Cleveland Medical Center/ Case Western Reserve University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1501: Thrombocytopenia in SLE: A Hidden Prognostic Marker of Increased Mortality and Adverse Outcomes - Results from Real World Data
Location: Hall F1
Abstract Poster Presenter: Milad Heydari-Kamjani, DO – University Hospitals Cleveland Medical Center/ Case Western Reserve University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1502: Prevalence and Associated Factors of Autoimmune Hepatitis and Primary Sclerosing Cholangitis in Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis
Location: Hall F1
Abstract Poster Presenter: Omer Pamuk, MD – University Hospitals Cleveland Medical Center/ Case Western Reserve University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1503: Lupus Disease Activity Adversely Affects the Quality of Life but not Intimate Relationship and Sexual Function in Indian Female Lupus Patients
1504: High prevalence of clonal hematopoiesis of indeterminate potential (CHIP) somatic mutations in a cohort of 1,073 SLE participants
Location: Hall F1
Abstract Poster Presenter: Richard Oppong, PhD – NATIONAL INSTITUTES OF HEALTH
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1505: Discordance Between Physician and Patient Global Assessment of Disease Activity in a Large Multicenter Prospective SLE Cohort in the U.S. and Canada
Location: Hall F1
Abstract Poster Presenter: Romy Kallas, MD, MS – Hospital for Special Surgery
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1506: Perspectives on Clinical Trial Participation for Novel Advanced Therapies: A Focus Group Study in Systemic Lupus Erythematosus (SLE)
Location: Hall F1
Abstract Poster Presenter: Sasha Bernatsky, MD,PhD – Research Institute of the McGill University Health Centre
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1507: Temporal Trends in the Incidence of Systemic Lupus Erythematosus (SLE) in the United States (US): Holding Steady?
Location: Hall F1
Abstract Poster Presenter: Sasha Bernatsky, MD,PhD – Research Institute of the McGill University Health Centre
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1508: Dissecting the Role of T Cell Subsets and Complements in Lupus Pathogenesis in Systemic Lupus Erythematosus Patients with Obesity
Location: Hall F1
Abstract Poster Presenter: Sheila Serin, MD – Ochsner Clinic Foundation
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1509: Outcome of Newly Diagnosed SLE with Serositis and Its Clinical Features in Daily Clinical Practice: A Single Center Study
1510: Biomarker landscape for neuropsychiatric involvement in patient with systemic lupus erythematosus
Location: Hall F1
Abstract Poster Presenter: Sitian Zang, n/a – Department of Rheumatology and Immunology, Peking University People’s Hospital
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1511: Mental Health and Medical Burden: The Impact of Depression on Length of Stay in Lupus Patients
Location: Hall F1
Abstract Poster Presenter: Sophia Chang Stauffer, MPH – Mount Sinai Hospital, Sinai Urban Health Institute and Univ.of Illinois @ Chicago, Dept Medicine, Div. Endocrinology
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1512: anti-u1-rnp Antibody Positivity Is Associated with Elevated Interferon Score in SLE Irrespective of Disease Activity: A Transcriptome Analysis in Japanese Patients
Location: Hall F1
Abstract Poster Presenter: Takemichi Matsui, MD – Icahn School of Medicine at Mount Sinai
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1513: Race, Renal Failure, and Risk: A five-to-ten year retrospective cohort study of Racial differences in outcomes of patients with dialysis-dependent Lupus nephritis
Location: Hall F1
Abstract Poster Presenter: Ufuoma Mamoh, MBChB – Medstar Georgetown University (Baltimore) Internal Medicine Residency
Abstract Poster Presenter: Yan Wang, n/a (she/her/hers) – Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1515: Machine Learning–defined Subtypes of Systemic Lupus Erythematosus Identify Distinct Immunologic and Molecular Signatures
Location: Hall F1
Abstract Poster Presenter: Yuke Hou, MD – Peking University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1517: The Chinese Experience with Telitacicept in Lupus Nephritis Management: 51-Patient Cohort Analysis on Therapeutic Outcomes and Safety Parameters
Location: Hall F1
Abstract Poster Presenter: Aijing Liu, PhD – Department of Rheumatology and Immunology, The Second Hospital of Hebei Medical University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1518: Efficacy and Safety of Anifrolumab in Discoid Lupus: A Meta-Analysis of the Literature
Location: Hall F1
Abstract Poster Presenter: Ali Ali, MD, RhMSUS – Department of Internal Medicine, Division of Rheumatology, Henry Ford Health System
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1519: Post-hoc Analysis of Sustained Response Over Time in Systemic Lupus Erythematosus Patients Treated with Cenerimod in CARE (Phase 2 B) Study
1520: Long-Term Effects of Obinutuzumab on Kidney Function in Lupus Nephritis
Location: Hall F1
Abstract Poster Presenter: Bahtiyar Toz, MD – Zucker School of Medicine at Hofstra/ Northwell
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1521: Kidney-Related Outcomes With Obinutuzumab in Patients With Active Lupus Nephritis: A Pre-Specified Exploratory Analysis of the Clinical Trial Data
Location: Hall F1
Abstract Poster Presenter: Brad Rovin, MD – The Ohio State University
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1522: Outcomes of Continuing Hydroxychloroquine following Renal Transplant in Patients with Lupus Nephritis: A retrospective Cohort Study using the TrinetX database
Location: Hall F1
Abstract Poster Presenter: Carlos Pena, MD – Jefferson Einstein Philadelphia
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1523: Genetic architecture and translational insights for SLE progression from preclinical stages
1529: Updated Phase 1 Trial Data Assessing the Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of BMS-986353 (CC-97540), a CD19-directed Chimeric Antigen Receptor T Cell Therapy Using a Next-Generation Process for Severe, Refractory SLE
1530: The Renal Activity Index for Lupus Identifies and Predicts Complete Renal Remission or Absence of Kidney Involvement in Systemic Lupus Erythematosus
1531: Achieving Remission and Low Disease Activity with Belimumab versus Placebo in Patients with SLE Excluding the Glucocorticoid Component from Target Definitions: A Post Hoc Analysis of Five Phase 3 Trials
Location: Hall F1
Abstract Poster Presenter: Ioannis Parodis, MD, PhD – Karolinska Institutet and Karolinska University Hospital, Department of Medicine Solna, Division of Rheumatology
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1532: Preliminary Safety, Efficacy, and Cellular Kinetics of CTA313, a CD19/BCMA Dual-Targeted Universal CAR-T Therapy, for Active Systemic Lupus Erythematosus
1536: Evaluating Systemic Lupus Erythematosus Remission Among Patients Initiating Belimumab in a Real-World Setting in the USA
Location: Hall F1
Abstract Poster Presenter: Aarat Patel, MD – GSK, US Medical Affairs
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1537: Local Immune effector Cell-Associated Toxicity Syndrome (LICATS) in CAR T-cell treated patients with Autoimmune Disease
Location: Hall F1
Abstract Poster Presenter: Melanie Hagen, MD (she/her/hers) – Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1538: Safety, Pharmacodynamics, and Efficacy of a Novel Plasmacytoid Dendritic Cells Targeting Antibody in Healthy Adults and Patients with SLE or Cutaneous Lupus Erythematosus with Active Skin Lesions: A First-In-Human Study of KK4277
Location: Hall F1
Abstract Poster Presenter: Minoru Hasegawa, MD;PhD – Division of Medicine, University of Fukui
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1539: The Impact Of Interferon Signature On Anifrolumab Efficacy And Safety In Systemic Lupus Erythematosus: A Systematic Review And Meta-analysis
1541: Tofacitinib versus Belimumab in maintenance therapy of Systemic Lupus Erythematosus: A Real-World Study of the CSTAR cohort
Location: Hall F1
Abstract Poster Presenter: Qizhi Yuan, PhD – Peking Union Medical College
Monday, Oct 27th
10:30 AM - 12:30 PM Central Time
1542: Alternative Definitions of Moderate Flares That Simulate Clinical Practice in Systemic Lupus Erythematosus: Post Hoc Exploration of Moderate Flares in Patients Treated with Dapirolizumab Pegol in a 48-week Phase 3 Trial
1545: Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: Interim Analysis of a Phase 3 Randomized Placebo-controlled Study
1552: Treatment With Anifrolumab Prevents Long-Term Cardiovascular Damage Accrual Compared With Real-World Standard of Care in Patients With Systemic Lupus Erythematosus: Findings From the LASER Study
1717: The Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) Predicts Mortality In Systemic Lupus Erythematosus (SLE) Patients: Data From The Almenara Lupus Cohort
1718: Mortality and Hematological Adverse Events in Patients with Cancer Receiving Immune Checkpoint Inhibitors: Impact of Pre-existing Systemic Lupus Erythematosus
Location: S102
Presenting Author: KEVIN SHENG- KAI MA, DDS – Center for Global Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States
Monday, Oct 27th
3:45 PM - 4:00 PM Central Time
1689: Addressing Perceived Discrimination in Lupus Care: Enhancing Patient Empowerment and Health Equity Through Education and Support
1719: Impact of SGLT2 Inhibitors on Cardiovascular Events, Mortality, and Lupus Nephritis in Patients with Systemic Lupus Erythematosus and Diabetes: Retrospective Cohort Study
1720: Comparison of Mortality Trends in Adults with Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus: A 21-Year Analysis Using CDC WONDER DATABASE.
Location: S102
Presenting Author: Khadija Mohib, MD – Kirk Kerkorian School of Medicine at UNLV
Monday, Oct 27th
4:15 PM - 4:30 PM Central Time
1691: Standardizing DXA Screening in Childhood-Onset Systemic Lupus Erythematosus at A Single Center: A Quality Improvement Initiative Using a Decision-Tree Algorithm
Location: W192A-C
Presenting Author: Andrea Gutierrez, BS – University of Texas Southwestern Medical School
Monday, Oct 27th
4:15 PM - 4:30 PM Central Time
1721: Excess Mortality in SLE Is Concentrated in Lupus Nephritis and aPL-Positive Subsets: A population-based inception cohort study
1838: Differential Expression Of Activation Markers On dsDNA-reactive B-cells Between Healthy Subjects And SLE Patients Reveals Unconventional Extrafollicular Activation In SLE
Location: Hall F1
Abstract Poster Presenter: Jolien Suurmond, PhD – Leiden University Medical Center
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
1839: Transcriptional Profiling of Whole Blood and Kidney Biopsy Samples from Lupus Nephritis and IgA Nephropathy Patients Suggests Different Disease Pathways
1842: Social Vulnerability Index, Type 2 Lupus Symptoms, and Select Dysregulated Immune Features Identify Stage 2 (Pre-classification) SLE in the Lupus Autoimmunity in Relatives (LAUREL) Follow-up Cohort
1843: Tissue Neutrophils in The Pathogenesis of Lupus Nephritis
Location: Hall F1
Abstract Poster Presenter: Norio Hanata, M.D., Ph.D. – Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
1844: Disease-Associated Macrophages Express an Injury-Associated Gene Program and Localize to Distinct Compartments in Proliferative and Mixed Histologic Classes of Lupus Nephritis
1847: Spatial transcriptomics reveals a complex microanatomic patterning of complement mediated inflammation and fibrosis in Class III pediatric lupus nephritis associated with local histologic injury
1848: DS-7011a, An Anti-TLR7 Antagonistic Monoclonal Antibody, Suppresses Human Immune Cells and Multiple Cytokines/Chemokines Related to the Pathogenesis of SLE
1850: First American SLE patients demonstrate enhanced lipid metabolism and B cell activation by high-content proteomic analyses
Location: Hall F1
Abstract Poster Presenter: Tayte Stephens, BS – University of Oklahoma Health Science Center
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
1851: Endotype Discovery in Systemic Lupus Erythematosus Using Multi-Omic Approaches: Toward Precision Insights into Cardiovascular and Renal Damage
Location: Hall F1
Abstract Poster Presenter: Tomás Cerdó, PhD – Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
1852: Cellular Landscape of Cutaneous Lupus Erythematosus Revealed by Single-Cell RNA Sequencing and Spatial Transcriptomics in the Lupus Accelerating Medicine Partnership Cohort
Location: Hall F1
Abstract Poster Presenter: Victoria Werth, MD – University of Pennsylvania
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
1853: SAP Expression in SLE T Cells is Associated with Differentiation Towards Pro-Inflammatory Effector Subsets.
2380: Factors Influencing Time to Diagnosis in Systemic Lupus Erythematosus: A Real-World Retrospective Analysis
Location: Hall F1
Abstract Poster Presenter: April Barnado, MD, MSc – Vanderbilt University Medical Center
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2381: Renal Tubular Complement C9 Deposition is Linked to Tubulointerstitial Fibrosis and Progression to Chronic Kidney Disease in Lupus Nephritis
Location: Hall F1
Abstract Poster Presenter: Angela Lu, BS – Albert Einstein College of Medicine
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2382: Autoimmune Hemolytic Anemia in SLE: A Real-World National Cohort Study
Location: Hall F1
Abstract Poster Presenter: Ansaam Daoud, MD – Case Western Reserve University/University Hospitals
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2383: The Age-Adjusted Charlson Comorbidity Index (CCI) Predicts All-Cause Mortality in Systemic Lupus Erythematosus (SLE) Patients: Data from the Almenara Lupus Cohort
2385: The Presence of Avascular Necrosis in Patients with Systemic Lupus Erythematosus Undergoing Total Knee Arthroplasty is Not Associated with Worse Outcomes
Location: Hall F1
Abstract Poster Presenter: Billy Kim, MD – Hospital for Special Surgery
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2386: anti-trim72 Auto-antibodies in Systemic Lupus Erythematosus Patients and a Lupus Mouse Model with Myocarditis Compromise Membrane Repair in Mouse & Human Cardiomyocytes
Location: Hall F1
Abstract Poster Presenter: Braden Zeno, BS – Ohio State University
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2387: Lupus Damage Index Revision – Item Generation and Reduction Phases
2391: Antinuclear Antibody Positivity in Patients with Psoriasis and Psoriatic Arthritis and the Risk of Developing Clinical Symptoms of SLE Following TNF Inhibitor Therapy
2396: A Machine Learning Algorithm Based on a 15-autoantibody Profile by a Novel Fully Automated Multiplexed Microarray Immunoassay for the Diagnosis of Autoimmune Connective Tissue Diseases
2397: Analytical Performance of a Fully Automated Multiplexed Microarray Immunoassay for the Simultaneous Detection of Fifteen Autoantibodies Associated with Connective Tissue Diseases in a Reference Laboratory in Southern France
2398: Analytical Performance of the hep-2 Substrate Diagnostic Kit for ANA as an Initial Step in the Evaluation of a Novel Fully Automated IFA Analyzer in a Laboratory in England
2399: Identification of an LN endotype linked to intestinal expansion of Pathogenic Strains of a Pathobiont Bacterium that induces Systemic Thrombo-inflammatory Pathways directly measurable in Urine
Location: Hall F1
Abstract Poster Presenter: Gregg Silverman, MD – NYU Grossman School of Medicine
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2400: Prevalence and Predictors of Types and Subtypes of Pulmonary Diseases in Systemic Lupus Erythematosus: A Population-Based Cross-Sectional Study Using High-Resolution Computed Tomography Scan and Pulmonary Function Testing
2401: Associations Between Serum Levels of Soluble Urokinase Plasminogen Activator Receptor (suPAR) and Activity and Chronicity Features in Diagnostic and Per-protocol Repeat Kidney Biopsies in Patients with Lupus Nephritis
Location: Hall F1
Abstract Poster Presenter: Ioannis Parodis, MD, PhD – Karolinska Institutet and Karolinska University Hospital, Department of Medicine Solna, Division of Rheumatology
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2402: High-Resolution Proteomic Profiling Validates BAFF Pathway Modulation and Reveals Novel Biomarker Signatures in Belimumab Treatment
Location: Hall F1
Abstract Poster Presenter: Ioannis Parodis, MD, PhD – Karolinska Institutet and Karolinska University Hospital, Department of Medicine Solna, Division of Rheumatology
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2403: Differential Risk of Inpatient Admissions Among SLE Subgroups: A Population-Based Analysis
2404: Clinical features of Elderly-onset Systemic Lupus Erythematosus
Location: Hall F1
Abstract Poster Presenter: Jessica Dai, BS – New York University Grossman School of Medicine
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2405: Machine Learning in SLE Diagnosis: Performance of the SLE Risk Probability Index Questionnaire in a Multicenter Cohort of Patients with Systemic Lupus Erythematosus
2406: Machine Learning-Based Artificial Intelligence in Systemic Lupus Erythematosus: A Systematic Review of Outcome Prediction and Patient Stratification
2407: Mapping Neurological Involvement, Regional Disparities, and Moderators of the Central Nervous System in Adult-Onset Systemic Lupus Erythematosus: A Global Systematic Review and Meta-Analysis
2416: Direct and Indirect Costs Associated with Damage Accrual: Results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort
2421: Whole Blood Immune Phenotyping Reveals Cytometric Differences in B Cell Clusters Between Lupus Nephritis and Non-Lupus Nephritis SLE Patients with Minimal Proteinuria
Location: Hall F1
Abstract Poster Presenter: Nicholas Bauer, BS – Oklahoma Medical Research Foundation
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2422: Cluster Analysis of Autoantibodies in Patients with Systemic Lupus Erythematosus
2427: Kidney-Specific Four-Protein Index Outperforms Conventional Measures for Detecting Early Kidney Damage in Lupus Nephritis and Diabetic Kidney Disease
2428: Differences in Dyspigmentation and Scarring Across Cutaneous Lupus Erythematosus Categories and Subtypes
Location: Hall F1
Abstract Poster Presenter: Shae Chambers, BA – University of Pennsylvania
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2429: mHealth-enabled Peer Coaching for Fatigue in Systemic Lupus Erythematosus (SLE): Preliminary Results from the Restore Energy, Activity Can Help (REACH) Pilot Randomized Controlled Trial
2441: Dapirolizumab Pegol Demonstrated Improvement in Quality of Life of Patients with Systemic Lupus Erythematosus: LupusQoL Results from a Phase 3 Trial
Location: Hall F1
Abstract Poster Presenter: Cynthia Aranow, MD – Feinstein Institutes for Medical Research
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2442: Reduction in Extrafollicular B Cell Responses in SLE Patients after CAR T Cell Therapy
2445: Achievement of Treat to Target Measures with Upadacitinib in Patients with Systemic Lupus Erythematosus: Phase 2 Randomized Sleek Clinical Trial Results
2449: Patient Characteristics, Treatment and Prognosis in Patients with Neuromyelitis OpticaSpectrum Disorder Coexisting with Systemic Lupus Erythematosus or Sjögren's Syndrome: An Analysis Using Japanese Inpatient Database
Location: Hall F1
Abstract Poster Presenter: Hiroshi Shiba, MD – Suwa central hospital
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2450: Spanish Real-World Ambispective Multicenter Registry of Anifrolumab in Systemic Lupus Erythematosus: Efficacy and Safety at 3- and 6-Month Follow-Up (ANIFRO-Reu Study)
2458: Obecabtagene autoleucel (obe-cel), a CD19-targeting Autologous Chimeric Antigen Receptor T-cell Therapy (CAR T) with a fast off-rate binding domain, in Patients (pts) with Severe, Refractory Systemic Lupus Erythematosus (srSLE): Preliminary Results from the Phase I CARLYSLE Study
2459: Hydroxychloroquine Discontinuation in Systemic Lupus Erythematosus: A Retrospective Cohort Study with 3-Year Follow-Up
Location: Hall F1
Abstract Poster Presenter: Milena Delai, MD – Beth Israel Deaconess Medical Center
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2460: Comparative Efficacy of Belimumab, Anifrolumab, and Rituximab in SLE: A Retrospective Analysis of Serological and Clinical Outcomes
Location: Hall F1
Abstract Poster Presenter: Pablo Martinez Calabuig, Sr, MD – HOSPITAL GENERAL UNIVERSITARIO VALENCIA SPAIN/ Escuela de doctoradoUniversidad Católica de Valencia San Vicente Mártir, Valencia, Spain
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2461: Targeting treatment-resistant Systemic Lupus Erythematosus through transcriptome-informed drug repurposing
Location: Hall F1
Abstract Poster Presenter: Panagiotis Garantziotis, MD – Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen
Tuesday, Oct 28th
10:30 AM - 12:30 PM Central Time
2462: Precision Dosing is Needed to Establish Predictable Exposure to the Active Metabolite of Mycophenolate Mofetil (MMF) in Pediatric Lupus Nephritis (LN)
Location: Hall F1
Abstract Poster Presenter: Pooja Patel, DO – Ann and Robert H. Lurie Children's Hospital of Chicago
2464: IMC-002 (IMM0306), a First-in-Class Bi-specific Fusion Protein, Demonstrates Improvements in Systemic Lupus Erythematosus (SLE) Disease Activity Measures and Biomarkers in Patients with Moderate to Severe Active SLE in the Open-label Phase 1b/2 Study
2465: CD19/BCMA Dual-Targeting FasTCAR-T Cells GC012F (AZD0120) in patients with refractory Systemic Lupus Erythematosusm: an open-label, single-center Phase I study
2467: Complete Renal Responses and Safety for Belimumab Versus Placebo in a Post Hoc Mycophenolate Mofetil Subgroup with Active Proliferative Lupus Nephritis
2597: Altered Tryptophan Metabolism in Neuropsychiatric Lupus: A Cluster Analysis to Identify Distinct Subgroups
Location: S103
Presenting Author: Yang Wu, MD, PhD – University of Washington; Chinese Academy of Medical Sciences & Peking Union Medical College
Tuesday, Oct 28th
1:15 PM - 1:30 PM Central Time
2598: Keratinocyte-Secreted Leukemia Inhibitory Factor Counteracts Type I IFN-Induced Antigen-Presenting Phenotype in Melanocytes: Utility in Cutaneous Lupus Skin
2599: Identification of a New Pathogenic Axis in Antiphospholipid Syndrome Linking Antiphospholipid Antibodies, Liver Function, and Circulating Proatherogenic Metabolites
Location: S103
Presenting Author: Beatriz Vellón-García, MSc – Department of Cell Biology, Physiology and Immunology, Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain.
Tuesday, Oct 28th
1:45 PM - 2:00 PM Central Time
2600: Deconstructing Lupus Nephritis Kidney Tissue at Single-Cell Resolution
2601: Characterisation of immunometabolic reprogramming at the single cell level in patients with systemic lupus erythematosus and preclinical autoimmunity
2645: Age-specific Incidence of Systemic Lupus Erythematosus in the United States: A Meta-analysis of Data from the Centers for Disease Control and Prevention Lupus Registries
Location: W192A-C
Presenting Author: Peter Izmirly, MD – New York University Grossman School of Medicine
Wednesday, Oct 29th
9:45 AM - 10:00 AM Central Time
2646: DNA methylation-based clustering reveals clinically distinct subtypes of systemic lupus erythematosus
Location: W192A-C
Presenting Author: Meghan Nelson, DO – National Institutes of Health
Wednesday, Oct 29th
10:00 AM - 10:15 AM Central Time
2647: Unlinked Paths to SLE: Divergent Associations of DNA Methylation and Polygenic Risk Scores with SLE Features
2648: Transcriptome analysis of quiescent SLE cases uncovers dysregulated pathways associated with disease flares
Location: W192A-C
Presenting Author: Lorenzo Beretta, MD – Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di MIlano
Wednesday, Oct 29th
10:30 AM - 10:45 AM Central Time
2649: Simultaneous Assessment of Complementary Lupus-Specific Immune Mediator-Informed Indexes Improves Their Ability to Concurrently Discern Current Disease Activity And Future Flare Risk In Systemic Lupus Erythematosus
2697: A Prospective Randomized Controlled 96-week Study to Evaluate the Efficacy and Safety of Tacrolimus and Glucocorticoid as Continuous Induction-maintenance Treatment for Class III/IV±V Lupus Nephritis
2694: Effect of Deucravacitinib Treatment on Renal Dysfunction–Associated Plasma Biomarkers From a Phase 2 Study in Patients With Systemic Lupus Erythematosus
2696: Biomarker Data From an Open-Label, Phase 1/2 Study for YTB323 (Rapcabtagene Autoleucel, a Rapidly Manufactured CD19 CAR-T Therapy) Suggest Reset of the B Cell Compartment in Severe Refractory SLE
2698: Comparative Efficacy of Tacrolimus-Based Induction Therapy with and without Mycophenolate Mofetil in Lupus Nephritis: A Target Trial Emulation Study
Location: W375C
Presenting Author: YUN KYU KIM, MD – Seoul National University