Shaun Jackson, MD, PhD
Seattle Children's Research Institute
Seattle, Washington, United States
Disclosure(s): Merck/MSD: Consultant (Ongoing)
Holly Wobma, MD;PhD
Boston Children's Hospital
Boston, MA, United States
Disclosure(s): No financial relationships with ineligible companies to disclose
Susan Shenoi, MS;MBBS;RhMSUS
Seattle Children's Hospital and Research Center
Mercer Island, WA, United States
Disclosure(s): AbbVie/Abbott: Consultant (Terminated); cabaletta: Consultant (Ongoing); sobi: Consultant (Ongoing)
Ekemini Ogbu, MD;MSc
Cincinnati Children's Hospital Medical Center
Cincinnati, OH, United States
Disclosure(s): No financial relationships with ineligible companies to disclose
This session will explore the emergence and potential impact of Chimeric Antigen Receptor (CAR) T-cell therapies in pediatric rheumatic diseases. It will provide a comprehensive overview of recent advancements in the field, with a focus on CAR T-cell therapy research in childhood-onset systemic lupus erythematosus and juvenile dermatomyositis. The session will also address the ethical and practical challenges associated with conducting cell-based therapy research in rare pediatric rheumatic diseases and discuss future opportunities for innovation and development in this area.
Speaker: Georg Schett, MD – Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany