We Are Not Getting Any Younger: Regulating Immune Responses During Inflammation and Aging

Moderator(s)

• CJ

  Caroline Jefferies, PhD

  Cedars-Sinai Medical Center
  Beverly Hills, CA, United States

  Disclosure(s): Amgen: Stock options or bond holdings in a for-profit corporation or self-directed pension plan (Ongoing); Eli Lilly: Stock options or bond holdings in a for-profit corporation or self-directed pension plan (Ongoing)
• BB

  Betsy Barnes, PhD

  Northwell Health
  Manhasset, NY, United States

  Disclosure information not submitted.

Session Coordinator(s)

• 

  Sadiq Umar, PhD

  University of Illinois at Chicago
  Chicago, IL, United States

  Disclosure(s): No financial relationships with ineligible companies to disclose

This session will define and discuss inflammaging - the chronic, low-grade inflammation that accompanies aging, and its role in the development and progression of rheumatic diseases. Mechanisms driving age-related immune dysfunction, their role in progression of rheumatic diseases, as well as a novel mechanisms to regulate macrophage function in rheumatic disease will be discussed.

Presentations:

• 1:00 PM - 1:30 PM Central Time

  Age-Related Naive T-Cell Remodeling
  

  Speaker: Maxim Artyomov, PhD – Washington University School of Medicine
• 1:30 PM - 2:00 PM Central Time

  Aging Blood from the Inside Out: How Megakaryocytes Shape Aging of the Immune System
  

  Speaker: Sandra Pinho
• 2:00 PM - 2:30 PM Central Time

  Transcription Control and Therapeutic Targeting of Macrophage Responses During Inflammation and Inflammatory Arthritis
  

  Speaker: Inez Rogatsky, PhD – Hospital for Special Surgery