Through the Looking Glass: Insights into the Pathogenesis of Autoimmune Uveitis

Moderator(s)

• 

  Margaret Chang, MD;PhD

  Boston Children's Hospital
  Boston, MA, United States

  Disclosure(s): No financial relationships with ineligible companies to disclose
• 

  Michael Paley, MD, PhD

  Washington University in St. Louis
  Saint Louis, MO, United States

  Disclosure(s): Priovant: Consultant (Terminated, March 31, 2024); UCB: Consultant (Terminated, November 30, 2023), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Terminated, November 30, 2023)

Session Coordinator(s)

• 

  Carla Cuda, PhD

  Northwestern University
  Chicago, IL, United States

  Disclosure information not submitted.

Non-infectious autoimmune uveitis is an inflammatory disorder of the eye that can emerge in isolation or from different systemic autoimmune and autoinflammatory diseases. While uveitis can be classified based on anatomic distribution, speed of onset, and associated systemic disease, we have little knowledge of the underlying pathophysiology to guide the choice of therapeutic intervention. This session provides new mechanistic insights into ocular inflammation.

Presentations:

• 10:30 AM - 11:00 AM Central Time

  Retinal Perivascular Macrophages Regulate Immune Cell Infiltration During Neuroinflammation in Ocular Disease
  

  Speaker: Jeremy Lavine, MD, PhD – Northwestern University
• 11:00 AM - 11:30 AM Central Time

  The Role of the Mammalian Commensal Intestinal Microbiota in Intestinal and Systemic Immunity Affecting the Development and Mitigation of Ocular Inflammation
  

  Speaker: Phoebe Lin, MD, PhD – Cleveland Clinic