Mary Beth Humphrey, MD, PhD
University of Oklahoma College of Medicine
Oklahoma City, Oklahoma, United States
Disclosure(s): No financial relationships with ineligible companies to disclose
Baohong Zhao, MD, PhD
Hospital for Special Surgery
New York, New York, United States
Disclosure information not submitted.
Baohong Zhao, MD, PhD
Hospital for Special Surgery
New York, New York, United States
Disclosure information not submitted.
Inflammatory bone loss is a signature feature and severe consequence of many inflammatory disorders, including inflammatory arthritis. The underlying mechanisms of bone resorption and metabolism in inflammatory settings are largely unknown. This session will highlight novel discoveries in inflammatory bone resorption.
Dr. George Hajishengallis will discuss how the clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss. Dr. Yousef Abu-Amer will discuss how DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8.
Speaker: Benjamin Alman, MD – Duke University
Speaker: Yousef Abu-Amer, PhD, MSc – Washington University School of Med