Bringing Sexy Back: Sex Hormone Modulation of Immune Responses in Autoimmunity

Moderator(s)

• 

  Melissa Cunningham, MD, PhD

  Medical University of SC
  Charleston, South Carolina, United States

  Disclosure(s): Allogene: Consultant (Ongoing)
• CJ

  Caroline Jefferies, PhD

  Cedars-Sinai Medical Center
  Beverly Hills, CA, United States

  Disclosure(s): Amgen: Stock options or bond holdings in a for-profit corporation or self-directed pension plan (Ongoing); Eli Lilly: Stock options or bond holdings in a for-profit corporation or self-directed pension plan (Ongoing)

Session Coordinator(s)

• CJ

  Caroline Jefferies, PhD

  Cedars-Sinai Medical Center
  Beverly Hills, CA, United States

  Disclosure(s): Amgen: Stock options or bond holdings in a for-profit corporation or self-directed pension plan (Ongoing); Eli Lilly: Stock options or bond holdings in a for-profit corporation or self-directed pension plan (Ongoing)

Autoimmune disease affects predominantly women, with greater than 90% of patients who are female in diseases such as lupus or Sjögren’s syndrome. This session will address how sex hormones influence immune responses and may potentially contribute to autoimmunity. It will investigate how sex hormones affect immune responses through the lens of gender-affirming care and obesity.

Presentations:

• 2:30 PM – 3:00 PM Central Time

  Obesity Influences Sex-Specific Interferon Signaling to Alter MS
  

  Speaker: Shannon Dunn, PhD – U Toronto and Sunnybrook Research Institute
• 3:00 PM – 3:30 PM Central Time

  Immune System Adaptation During Gender-Affirming Testosterone Treatment
  

  Speaker: Petter Brodin, MD, PhD – Karolinska Institut