27M19: Abstracts: Rheumatoid Arthritis – Animal Models (0867–0872)

Abstract Moderator(s)

• SM

  Susan MacLauchlan, PhD

  Brigham and Women's Hospital
  Boston, Massachusetts, United States

  Disclosure information not submitted.
• MC

  Maripat Corr, MD

  ucsd
  San Diego, CA, United States

  Disclosure information not submitted.

Presentations:

• 10:00 AM - 10:15 AM Central Time

  NLRP3 Inflammasome Impairs Fracture Repair in Rheumatoid Arthritis through RhoA/Rac1-IL1β Axis-Mediated Suppression of Osteoblast Differentiation
  

  Presenting Author: WEN SUN, PhD – Nanjing Medical University
• 10:30 AM - 10:45 AM Central Time

  PD-1 inhibitor unleashes pathogenic CD8+ T cells and induce arthritis in collagen-primed mice
  

  Presenting Author: Sang Kim, MD – Yale University
• 10:45 AM - 11:00 AM Central Time

  Same Model, Different Results: Vendor and Microbiome Influence Reproducibility in Collagen Induced Arthritis
  

  Presenting Author: Brenda Seymour, PhD – University of Colorado
• 11:00 AM - 11:15 AM Central Time

  The gut microbiome shapes MTX pharmacology and is linked to treatment outcomes
  

  Presenting Author: Renuka Nayak, MD, PhD – University of California, San Francisco (UCSF)
• 11:15 AM - 11:30 AM Central Time

  Silencing of Schnurri-3 protects from TNF-induced bone loss and is accompanied by upregulation of type I Interferon-Stimulated Genes (ISGs) in osteoblasts.
  

  Presenting Author: Priyanka Kushwaha, PhD – Brigham and Women's Hospital