(0067–0097) Rheumatoid Arthritis – Etiology and Pathogenesis Poster

Sunday, October 26, 2025

10:30 AM - 12:30 PM Central Time

Location: Hall F1

CE: 0.00

Presentations:

10:30 AM - 12:30 PM Central Time

Aberrant Histone Marks Increase the Inflammatory Phenotype of Rheumatoid Arthritis Fibroblast-like Synoviocytes (RA FLS) by Suppressing NUB1 Induction
Abstract Poster Presenter: Yosuke Ono, PhD – UCSD
10:30 AM - 12:30 PM Central Time

Androgen Upregulates Interferon Signaling in Osteoclast Differentiation During Inflammatory State
Abstract Poster Presenter: Kiana Chen, PhD – University of Rochester School of Medicine and Dentistry
10:30 AM - 12:30 PM Central Time

Antibodies to Malondialdehyde-acetaldehyde Are Associated with Circulating Inflammatory Mediators During the Preclinical Stages of Rheumatoid Arthritis
Abstract Poster Presenter: Emma Weis, BS – University of Nebraska Medical Center
10:30 AM - 12:30 PM Central Time

Association of Protein Arginine Deiminase 4 with the myosin-9 Motor Complex
Abstract Poster Presenter: Fatemeh (Neela) Moadab, MD (she/her/hers) – University of Washington
10:30 AM - 12:30 PM Central Time

Citrullinated Serum Albumin Is Not an Autoantigen in Rheumatoid Arthritis
Abstract Poster Presenter: Farheen Sultan Shaikh, PhD (she/her/hers) – University of Washington
10:30 AM - 12:30 PM Central Time

Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Rheumatoid Arthritis: associations with treatment response and comorbidities
Abstract Poster Presenter: Mihir Wechalekar, MD, PhD, FRACP – Flinders Medical Centre and Flinders University
10:30 AM - 12:30 PM Central Time

Confirmatory Factor Analysis of the Plutchik Suicide Risk Scale in Patients with Rheumatoid Arthritis
Abstract Poster Presenter: Juliana Muñoz Bedoya, MD – Juan N Corpas University Foundation
10:30 AM - 12:30 PM Central Time

Distinct immune-molecular signatures modulated ex vivo by JAK and TNF predict Rheumatoid Arthritis therapy outcomes in patients naïve to biologic and targeted synthetic DMARDs
Abstract Poster Presenter: Sagrario Corrales Díaz-Flores, -None- – IMIBIC
10:30 AM - 12:30 PM Central Time

Effect of JAK Inhibitors on Osteoblast Differentiation
Abstract Poster Presenter: Toshihiro Tanioka, PhD – Showa Medical University
10:30 AM - 12:30 PM Central Time

Expansion of PD-1^hi Tfh and Tph cells in the peripheral blood of seropositive clinically suspect arthralgia patients: association with progression to rheumatoid arthritis
Abstract Poster Presenter: Maria-Eugenia Miranda-Carus, MD,PhD (she/her/hers) – Hospital Universitario La Paz
10:30 AM - 12:30 PM Central Time

GLUT1-Dependent Targeting and Enhanced Selectivity of a Glucose-Methotrexate Conjugate in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
Abstract Poster Presenter: Wojciech Tański, MD, PhD (he/him/his) – Wrocław University of Science and Technology
10:30 AM - 12:30 PM Central Time

HLA-DQA1*01:02 Is Associated With IgG Multi-Reactivity With Citrulline-Containing Type II Collagen Epitopes While HLA-DRB*04:01 Is Associated With More Private Reactivity With Citrulline-Containing IgG Epitopes In Rheumatoid Arthritis
Abstract Poster Presenter: Courtney Myhr, MS – University of Wisconsin-Madison
10:30 AM - 12:30 PM Central Time

IBI3011, a Humanized anti-IL1RAP Monoclonal Antibody, Inhibits IL1, IL33, IL36-driven Inflammation Pathway, and Attenuates Inflammation in Preclinical Inflammatory Disease Model
Abstract Poster Presenter: Jinyang Li, PhD (he/him/his) – Innovent Biologics (Suzhou) Co., Ltd.
10:30 AM - 12:30 PM Central Time

Identification of Neutrophil Extracellular Traps in Explanted Human Lungs with Rheumatoid Arthritis-related Interstitial Lung Disease
Abstract Poster Presenter: Amara Seng, MD, PhD (she/her/hers) – Cedars-Sinai Medical Center
10:30 AM - 12:30 PM Central Time

Imbalance of Inflammation-Regulating Microorganisms and Predicted Metabolomic Pathways Associates With Disease Evolution in Individuals At-Risk for Rheumatoid Arthritis
Abstract Poster Presenter: Lyndsey Cole, MD – University of Colorado School of Medicine
10:30 AM - 12:30 PM Central Time

Impact of Baricitinib on Cardiovascular Health in Biologic-naïve Rheumatoid Arthritis patients: A Comparative Study with TNF Inhibitors and Conventional DMARDs
Abstract Poster Presenter: Chary Lopez-Pedrera, PhD – IMIBIC - Reina Sofia Hospital
10:30 AM - 12:30 PM Central Time

Impact of CXCL2 and IL-11 from Rheumatoid Arthritis Synovial Fibroblasts on Angiogenesis and Endothelial Cell Network Formation
Abstract Poster Presenter: Elena Neumann, PhD (she/her/hers) – JLU Gießen, Campus Kerckhoff
10:30 AM - 12:30 PM Central Time

Integrating Synovial Protein Signatures and Serum Profiles to Predict Disease Activity and Treatment Response in Early Rheumatoid Arthritis
Abstract Poster Presenter: Chary Lopez-Pedrera, PhD – IMIBIC - Reina Sofia Hospital
10:30 AM - 12:30 PM Central Time

Integrative Metabolomic and Inflammatory Profiling in Rheumatoid Arthritis: Disease activity, therapeutic modulation, and underlying hepatic mechanisms
Abstract Poster Presenter: Laura Muñoz-Barrera, BSc – IMIBIC/Reina Sofia Hospital/University of Cordoba
10:30 AM - 12:30 PM Central Time

Interleukin-36β modulates the progression of rheumatoid arthritis by altering the behavior of rheumatoid arthritis synovial fibroblasts
Abstract Poster Presenter: Marie Kümmel, MS (she/her/hers) – Justus-Liebig University
10:30 AM - 12:30 PM Central Time

Regulation of the same chemokine gene transcription by different histone lysine methyltransferases, MLL1 and MLL3, in rheumatoid arthritis synovial fibroblasts
Abstract Poster Presenter: Keita Okamoto, MD;PhD – Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University
10:30 AM - 12:30 PM Central Time

Rheumatoid Factors (RFs) in RA Patient Sera Do Not Bind To Fc-Free Certolizumab Pegol, But Do Bind To Fc-Containing Anti-TNF-α Biological DMARDs, Driving Immune Complex Formation and Cellular Clearance
Abstract Poster Presenter: David Humphreys, PhD;BSc (he/him/his) – UCB Pharma
10:30 AM - 12:30 PM Central Time

Single Cell RNA-seq Revealed Immune/epithelial Cell Abnormalities Underlying the Pathogenesis of Rheumatoid Arthritis-related Interstitial Lung Disease
Abstract Poster Presenter: Kensuke Suga, PhD – Cedars-Sinai Medical Center
10:30 AM - 12:30 PM Central Time

Soluble CD13 engages protease-activated receptor 4 to promote synovial inflammation and angiogenesis in rheumatoid arthritis
Abstract Poster Presenter: Eliza Pei-Suen Tsou, PhD (she/her/hers) – University of Michigan
10:30 AM - 12:30 PM Central Time

Spatial transcriptomics in rheumatoid arthritis (RA) synovium reveals distinct region-specific fibroblast functions
Abstract Poster Presenter: Camilla Machado, PhD – UCSD
10:30 AM - 12:30 PM Central Time

SynovAI: A Revolutionary AI Framework for Enhanced Detection and Differentiation of Rheumatoid Arthritis, Osteoarthritis, and Spondyloarthritis via Advanced Ultrasound Imaging
Abstract Poster Presenter: Mojtaba S. Fazli, PhD – Stanford University
10:30 AM - 12:30 PM Central Time

The Role of DICAM in Modulating Macrophage Differentiation and Inflammatory Responses via αvβ3 Integrin Signaling in Rheumatoid Arthritis
Abstract Poster Presenter: HANNA LEE, MD – Changwon Gyeongsang National University Hospital
10:30 AM - 12:30 PM Central Time

Trans-endothelial Trafficking of Fibroblast-like Synoviocytes Amplifies Synovial Inflammation in Rheumatoid Arthritis
Abstract Poster Presenter: Jaeyeon Kim, PhD – Cedars Sinai Medical Center
10:30 AM - 12:30 PM Central Time

Transformer-based multi-omics study identifies important role of glycine, serine and threonine metabolism pathway in rheumatoid arthritis complicated by anemia
Abstract Poster Presenter: Fanxin Zeng, PhD – Departmant of Clinical Research Center, Sichuan Clinical Research Center for Medical Imaging, Dazhou Central Hospital
10:30 AM - 12:30 PM Central Time

Unique Fibroblast-like Synoviocyte Phenotype with Elevated MCSF Expression Induced by TLR5 Activation in Rheumatoid Arthritis
Abstract Poster Presenter: Aryan Patel, BA – University of Illinois at Chicago
10:30 AM - 12:30 PM Central Time

Unravelling Transcriptomic Landscapes in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Shared and Unique Molecular Signatures related to relevant clinical features.
Abstract Poster Presenter: Chary Lopez-Pedrera, PhD – IMIBIC - Reina Sofia Hospital