(1855–1876) Systemic Sclerosis & Related Disorders – Basic Science Poster II

Tuesday, October 28, 2025

10:30 AM - 12:30 PM Central Time

Location: Hall F1

CE: 0.00

Presentations:

10:30 AM - 12:30 PM Central Time

GLUT and FAPα as molecular imaging markers for interstitial lung disease in systemic sclerosis
Abstract Poster Presenter: Bo Broens, MD – Amsterdam UMC
10:30 AM - 12:30 PM Central Time

Role of autoantigen-specific reactivity in the pathogenesis of murine interstitial lung disease model with anti-MDA5 antibody mouse model
Abstract Poster Presenter: Atsubumi Ogawa, MD – Kyoto University
10:30 AM - 12:30 PM Central Time

Spatial Proteomic-based Phenotyping of Fibroblast Populations and their Microenvironment in Systemic Sclerosis Primary Heart Involvement
Abstract Poster Presenter: Andrea-Hermina Györfi, MD – Department of Rheumatology, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University.
10:30 AM - 12:30 PM Central Time

Deciphering the Molecular Landscape of the Small Intestine in Early and Late SSc Using High-Definition Spatial Transcriptomics
Abstract Poster Presenter: Laura Much, MSc – Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich
10:30 AM - 12:30 PM Central Time

Accelerated and Gene-specific Patterns of Clonal Hematopoiesis Distinguish Subtypes of Systemic Sclerosis
Abstract Poster Presenter: Brecca Miller, n/a (she/her/hers) – Center for Human Genetics and Genomics, NYU Grossman School of Medicine
10:30 AM - 12:30 PM Central Time

Paracrine WNT Signaling Modulates Profibrotic Macrophage Metabolic Activation in Systemic Sclerosis
Abstract Poster Presenter: Patricia Pioli, PhD – Geisel School of Medicine at Dartmouth
10:30 AM - 12:30 PM Central Time

Fcγ-receptor activation by circulating immune complexes in autoimmunity and CD19.CAR-T cell therapy
Abstract Poster Presenter: Wolfgang Merkt, MD – University Hospital Düsseldorf
10:30 AM - 12:30 PM Central Time

bag3 in Systemic Sclerosis: Possible Therapeutic Target and Biomarker for Pulmonary Fibrosis
Abstract Poster Presenter: Claudia Iannone, MD – University of Milan, Gaetano Pini CTO
10:30 AM - 12:30 PM Central Time

High-throughput Screening Uncovers Distinct Molecular Signatures Linked with HRCT Patterns in SARD-ILD
Abstract Poster Presenter: Philip Stauffer, PhD – University of Zurich Hospital
10:30 AM - 12:30 PM Central Time

Mitochondrial Dysfunction Drives cGAS-STING–Mediated Type I Interferon Production and Fibrosis in Systemic Sclerosis
Abstract Poster Presenter: Giulio Forte, n/a – Università della Campania Luigi Vanvitelli
10:30 AM - 12:30 PM Central Time

Elucidating gastric pathology in systemic sclerosis using single-cell RNA sequencing
Abstract Poster Presenter: Kristina Clark, PhD, MBBS, MRCP – University of Oxford
10:30 AM - 12:30 PM Central Time

Neutrophil Extracellular Trap-Rich Systemic Sclerosis Plasma Promotes Microvascular Endothelial Cell Proliferation and Migration: Implications for Aberrant Angiogenesis
Abstract Poster Presenter: Wenying Liang, PhD, MBBS – University of Michigan
10:30 AM - 12:30 PM Central Time

Global Downregulation of Fli1 in Mice Induces Cardiac Dysfunction via Enhanced β-fatty acid Oxidation and Collagen Deposition
Abstract Poster Presenter: Moyo Mudhibadhi, PhD (he/him/his) – Boston University
10:30 AM - 12:30 PM Central Time

Unraveling Disparities in Systemic Lupus Erythematosus-Related Mortality Among U.S. Adults (≥25 Years) with Malignancy: A Longitudinal Analysis of Gender, Race, and Geographic Inequities Using CDC WONDER (1999–2020)"
Abstract Poster Presenter: Ayesha Khan, n/a – Dow Medical College
10:30 AM - 12:30 PM Central Time

TGF-β-Driven Mitochondrial Stress Activates cGAS-STING Signalling via Impaired Mitophagy in Systemic Sclerosis Endothelial Cells
Abstract Poster Presenter: Stefano Di Donato, MD – University of Leeds
10:30 AM - 12:30 PM Central Time

Examining the Impact of ETV2 on altered endothelial phenotype in systemic sclerosis
Abstract Poster Presenter: Eliza Pei-Suen Tsou, PhD (she/her/hers) – University of Michigan
10:30 AM - 12:30 PM Central Time

Targeting the NK cell checkpoint NKG2A promotes lung fibrosis resolution by enhancing immune clearance of senescent myofibroblasts
Abstract Poster Presenter: Wolfgang Merkt, MD – University Hospital Düsseldorf
10:30 AM - 12:30 PM Central Time

Shared and unique molecular signatures across different autoantibody groups in systemic sclerosis: a multi-omics analysis
Abstract Poster Presenter: Hanlin Yin, MD, PhD – Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital
10:30 AM - 12:30 PM Central Time

Antinuclear Antibodies from Systemic Sclerosis Patients Enter Cells via a Clathrin Endocytosis Mechanism and Interact with Their Intracellular Antigen
Abstract Poster Presenter: Aurélien Chepy, -None- (he/him/his) – INFINTE U186 inserm, univeristy of Lille
10:30 AM - 12:30 PM Central Time

Comprehensive analysis of the major histocompatibility complex in systemic sclerosis-associated interstitial lung disease identifies novel associated loci and potential progression biomarkers
Abstract Poster Presenter: Carlos de la Rosa Báez, MSc – Department of Cell Biology and Immunology, Institute of Parasitology and Biomedicine López-Neyra, CSIC
10:30 AM - 12:30 PM Central Time

Small Bowel Microbial Dysbiosis and Impaired Intestinal Absorptive Function in Systemic Sclerosis- A Single Center Prospective Study
Abstract Poster Presenter: Adam Edwinson, PhD – Mayo Clinic
10:30 AM - 12:30 PM Central Time

A Mirna Signature Consisting of High let7i-5p, High mir-483-5p, Low mir-223- 3p Characterizes Connective Tissue Diseases with Interstitial Lung Disease
Abstract Poster Presenter: Olga Sanchez Pernaute, MD,PhD (she/her/hers) – Clinica Universidad de Navarra