(1780–1808) Osteoarthritis & Joint Biology – Basic Science Poster

Tuesday, October 28, 2025

10:30 AM - 12:30 PM Central Time

Location: Hall F1

CE: 0.00

Abstract poster session - 29 abstracts.

Presentations:

10:30 AM - 12:30 PM Central Time

Clearance Kinetics and Cartilage Retention of MM-II, a Dispersion of Large Empty Liposomes, in Rat Knees
Abstract Poster Presenter: Roni Wechsler, PhD – Moebius Medical
10:30 AM - 12:30 PM Central Time

Determining the Effect of CD14 Deficiency on Osteoblastogenesis and Subchondral Bone Remodeling In Mice
Abstract Poster Presenter: Lance Murphy, -None- – University of Pennsylvania Perelman School of Medicine
10:30 AM - 12:30 PM Central Time

Human meniscus histopathological and transcriptomic changes at early and advanced stages of knee osteoarthritis
Abstract Poster Presenter: Takuya Sakamoto, MD, PhD – Scripps Research Institute
10:30 AM - 12:30 PM Central Time

Lightsheet imaging with 3D analysis for wholistic assessment of synovial lymphatic vasculature within joints of murine models of arthritis
Abstract Poster Presenter: Xi Lin, PhD – University of Rochester Medical Center
10:30 AM - 12:30 PM Central Time

Manganese-associated Single-nucleotide Polymorphisms are Associated with Radiographic Knee Osteoarthritis: The Johnston County Osteoarthritis Project
Abstract Poster Presenter: Griffin Sonaty, MD, MPH – University of North Carolina
10:30 AM - 12:30 PM Central Time

Mapping The Synovial Innervation Of The Human Knee Joint
Abstract Poster Presenter: Alia Obeidat, PhD – Rush University Medical Center
10:30 AM - 12:30 PM Central Time

Matrikine Activation of Synovial Fibroblasts Promotes Monocyte Migration and Stimulates an OA Chondrocyte Phenotype
Abstract Poster Presenter: Richard F. Loeser, Jr, MD, MACR – University of North Carolina
10:30 AM - 12:30 PM Central Time

Modeling Osteoarthritis Knee Joint in a Compartmentalized Microfluidic System using IPSC-derived Sensory Neurons and human Synovial Fibroblasts
Abstract Poster Presenter: Abdelhak Belmadani, n/a (he/him/his) – Northwestern University Chicago
10:30 AM - 12:30 PM Central Time

Multimodal Preclinical Screening Of Glucocorticoid-Induced Disruption Of Bone Remodeling In Rat
Abstract Poster Presenter: Anik Tuladhar, PhD (he/him/his) – AbbVie
10:30 AM - 12:30 PM Central Time

Multi-Tissue Molecular and Histopathological Profiling of Facet Joints and Intervertebral Discs
Abstract Poster Presenter: Nashrah Ahmad, PhD – Scripps Research
10:30 AM - 12:30 PM Central Time

Nerve Growth Factor Causes Sensitization, Nociceptor Sprouting, Synovitis, And Osteophyte Formation In Naïve Murine Joints
Abstract Poster Presenter: Alia Obeidat, PhD – Rush University Medical Center
10:30 AM - 12:30 PM Central Time

OA protection in African spiny (Acomys) mice is partially mediated by the gut microbiome and is transferrable to wild-type mice via microbiome transplantation
Abstract Poster Presenter: Matlock Jeffries, MD, FACP, FACR – Oklahoma Medical Research Foundation
10:30 AM - 12:30 PM Central Time

OA-associated pain sensitivity is reduced in OA-protected MRL/MpJ mice, partially mediated by the gut microbiome, and transferable via microbiome transplantation
Abstract Poster Presenter: Montana Barrett, BS – University of Oklahoma
10:30 AM - 12:30 PM Central Time

Patching of Damaged Meniscus and Cartilage of Osteoarthritic Animals by MM-II, a Dispersion of Empty Large Multilamellar Liposomes
Abstract Poster Presenter: Roni Wechsler, PhD – Moebius Medical
10:30 AM - 12:30 PM Central Time

Pharmacology of LEVI-04, a novel treatment for OA
Abstract Poster Presenter: Simon Westbrook, PhD – Levicept Ltd
10:30 AM - 12:30 PM Central Time

Proteomic Profiling of Chondrogenic Gene Therapy in Human MSCs Reveals Distinct Regenerative Pathways for Articular Cartilage Repair
Abstract Poster Presenter: Patricia Quaranta, PhD – INIBIC
10:30 AM - 12:30 PM Central Time

SEV 101 Exosomes Isolated from Induced Pluripotent Stem Cell Derived Hyaline Cartilage Tissue Characterization of Immunomodulatory and Chondroproliferative Effects In Vitro
Abstract Poster Presenter: Parthasarathy Rangarajan, PhD – Medical School, UMN
10:30 AM - 12:30 PM Central Time

SEV-101, A Regenerative Exosome Therapeutic for the Treatment of Osteoarthritis
Abstract Poster Presenter: Beth Lindborg, MS, MBA – Sarcio, Inc.
10:30 AM - 12:30 PM Central Time

Sex differences in knee joint microbial DNA of C57BL/6 mice and the effect of cross-sex microbiome transplantation
Abstract Poster Presenter: Veera Durga Vaishnavi Kurra, MD – University of Oklahoma Health Sciences Center
10:30 AM - 12:30 PM Central Time

Sex-associated changes to synovial macrophages in the aging joint
Abstract Poster Presenter: Matthew Dapas, PhD – Northwestern University
10:30 AM - 12:30 PM Central Time

Soluble CD14 Amplifies Chondrocyte Inflammatory Responses to Lipopolysaccharide and Is Targetable by Anti-CD14 Therapy
Abstract Poster Presenter: Anna Rapp, PhD – University of Pennsylvania
10:30 AM - 12:30 PM Central Time

Spatial Analysis of Advanced Osteoarthritis Synovial Tissue
Abstract Poster Presenter: jacob Dickman, n/a – Medical College of Wisconsin
10:30 AM - 12:30 PM Central Time

Spatial and Quantitative Semiautomated Image Analysis of Synovial Biopsies Studied Using a Novel High-Plex Immunofluorescence Platform
Abstract Poster Presenter: Estefania Quesada-Masachs, MD, PhD – University of Miami
10:30 AM - 12:30 PM Central Time

Specific gut microbiome remodeling occurs after induction of OA via DMM surgery compared to sham surgery
Abstract Poster Presenter: Aleksander Szymczak, PhD – Oklahoma Medical Research Foundation
10:30 AM - 12:30 PM Central Time

Targeted Ablation of Knee-innervating Nociceptors Attenuates Pain and Cartilage Degeneration in Experimental Osteoarthritis
Abstract Poster Presenter: Lai Wang, MD;PhD – Rush University Medical Center
10:30 AM - 12:30 PM Central Time

The Role of Nociceptor-Expressed Piezo2 in Nervous System Immune Cell Infiltration in a Mouse Model of Osteoarthritis
Abstract Poster Presenter: Rachel Miller, PhD, BS – Rush University Medical Center
10:30 AM - 12:30 PM Central Time

Trends and Disparities in Osteoarthritis-Related Mortality in the United States: A 21-Year Analysis (1999-2020)
Abstract Poster Presenter: muzamil Khan, MBBS – George Washington University School of Medicine and Health Sciences
10:30 AM - 12:30 PM Central Time

Validating the Gouty Arthritis Alleviating Effects of Cerevisterol through Integrated In Silico, In Vitro, and In Vivo Studies
Abstract Poster Presenter: Qiang Xu, n/a – Guangzhou University of Traditional Chinese Medicine