(0934–0954) Systemic Lupus Erythematosus – Animal Models Poster

Monday, October 27, 2025

10:30 AM - 12:30 PM Central Time

Location: Hall F1

CE: 0.00

Presentations:

10:30 AM - 12:30 PM Central Time

A Novel Preclinical Tool for Evaluating CD20 Antibody Efficacy Based on BAFF/CD20 Dual-target Humanized Mice
Abstract Poster Presenter: Juan Liang, DrPH – Gempharmatech
10:30 AM - 12:30 PM Central Time

Ep300-Catalyzed Rad50 Lactylation Compromises Genomic Stability and Drives CD4+T cells Cell Senescence in SLE
Abstract Poster Presenter: mingyang zhang, n/a (he/him/his) – Daping Hospital, Army Medical University
10:30 AM - 12:30 PM Central Time

Epidermal IFNκ Increases Circulating and Cutaneous Monocytes in a C57/Bl6 Overexpression Mouse Model
Abstract Poster Presenter: Patrick O'Brien, BS (he/him/his) – University of Michigan
10:30 AM - 12:30 PM Central Time

Exploring the Mechanism of Action and Related Biomarkers of BTK Inhibitor/Degrader in Systemic Lupus Erythematosus
Abstract Poster Presenter: Chengfeng Xue, PhD (he/him/his) – WuXi AppTec
10:30 AM - 12:30 PM Central Time

In Vivo PanCAR Therapy Utilizing Circular RNA for Treatment of Autoimmune Diseases
Abstract Poster Presenter: Isin Dalkilic-Liddle, PhD – Orna Therapeutics
10:30 AM - 12:30 PM Central Time

L-sepiapterin treatment reduces renal cortical gene expression associated with oxidative stress and fibrosis in NZM2410 murine lupus nephritis
Abstract Poster Presenter: Jim Oates, MD – Medical University of South Carolina
10:30 AM - 12:30 PM Central Time

Mechanisms of anti-NMDAR antibody-mediated neuronal pathology and mitigation by angiotensin II signaling inhibition
Abstract Poster Presenter: Kaitlin Carroll, PhD – Institute of Molecular Medicine, The Feinstein Institutes for Medical Research
10:30 AM - 12:30 PM Central Time

MRL-lpr Mice Display Altered Nociception: A new model for lupus peripheral neuropathy
Abstract Poster Presenter: Chaim Putterman, MD – Albert Einstein College of Medicine
10:30 AM - 12:30 PM Central Time

Nerve Injury-Induced Protein-1 (Ninj1) Deficiency Aggravates Murine Lupus Through Modulation of Macrophage Polarization
Abstract Poster Presenter: Jorge Romo-Tena, MD, PhD – NIH
10:30 AM - 12:30 PM Central Time

NMDAR Autoantibody-Induced Neuronal Damage in the Amygdala Mediates Mood and Anxiety Disorders in a Model of Neuropsychiatric Lupus
Abstract Poster Presenter: Rachel Weissman-Tsukamoto, BS, MAT – Feinstein Institute of Molecular Medicine
10:30 AM - 12:30 PM Central Time

Oral Antibiotic Treatment Reduces Anxiety in a Murine Model of Neuropsychiatric Manifestations of Systemic Lupus Erythematosus
Abstract Poster Presenter: Cecilia Stumpf, BA – Northwestern University
10:30 AM - 12:30 PM Central Time

Presentation of Apoptotic Cell-Derived Autoantigens in Systemic Autoimmune Disease
Abstract Poster Presenter: Lance Peterson, MD, PhD – Washington University in St Louis
10:30 AM - 12:30 PM Central Time

Resident Macrophages Localize Near Fibroblasts and Drive Reprogramming in Lupus Nephritis Through Direct and Soluble Signaling
Abstract Poster Presenter: Chirag Raparia, PhD, MS, BS (he/him/his) – Donald and Barbara Zucker School of Medicine At Hofstra/Northwell
10:30 AM - 12:30 PM Central Time

Short Term Antibiotic Treatment Improves the Neurobehavioral Phenotype of MRL/lpr Mice
Abstract Poster Presenter: Chaim Putterman, MD – Albert Einstein College of Medicine
10:30 AM - 12:30 PM Central Time

Sodium-Glucose Co-Transporter 2 Inhibitors Modulate Renal Injury and Autoreactive Plasma Cells in Lupus
Abstract Poster Presenter: Jennifer Nicholson, BS (she/her/hers) – University of Rochester
10:30 AM - 12:30 PM Central Time

The Cancer-associated Female-biased Factor VGLL3 Drives Autoimmunity and Fibrosis
Abstract Poster Presenter: Mehrnaz Gharaee-Kermani, DVM, MPH, PhD – University of Michigan
10:30 AM - 12:30 PM Central Time

The Use Of Preclinical Models To Understand Drivers Of Lupus Pathogenesis
Abstract Poster Presenter: Arielle Glatman Zaretsky, PhD – Regeneron
10:30 AM - 12:30 PM Central Time

Therapeutic Potential of PaPE-1 in Reducing TLR7-Mediated Inflammation in a Murine Model of Lupus
Abstract Poster Presenter: Rachael Werner, MD, PhD – Medical University of South Carolina
10:30 AM - 12:30 PM Central Time

Type I and Type II IFNs have both independent and overlapping effects on SLE disease severity
Abstract Poster Presenter: Jeremy Tilstra, MD, PhD – University of Pittsburgh
10:30 AM - 12:30 PM Central Time

Ultrasound-Mediated Blood–Brain Barrier Permeabilization Enables Targeted Drug Delivery in a Murine Model of Neuropsychiatric SLE
Abstract Poster Presenter: Chaim Putterman, MD – Albert Einstein College of Medicine