Shaun Jackson, MD, PhD
Seattle Children's Research Institute
Seattle, Washington, United States
Disclosure(s): Merck/MSD: Consultant (Ongoing)
Holly Wobma, MD, PhD
Boston Children's Hospital
Boston, Massachusetts, United States
Disclosure(s): No financial relationships with ineligible companies to disclose
Susan Shenoi, MBBS, MS, RhMSUS
Seattle Children's Hospital and Research Center
Mercer Island, WA, United States
Disclosure(s): AbbVie/Abbott: Consultant (Terminated); cabaletta: Consultant (Ongoing); sobi: Consultant (Ongoing)
Ekemini Ogbu, MD, MSc
Cincinnati Children's Hospital Medical Center
Cincinnati, OH, United States
Disclosure information not submitted.
This session will explore the emergence and potential impact of Chimeric Antigen Receptor (CAR) T-cell therapies in pediatric rheumatic diseases. It will provide a comprehensive overview of recent advancements in the field, with a focus on CAR T-cell therapy research in childhood-onset systemic lupus erythematosus and juvenile dermatomyositis. The session will also address the ethical and practical challenges associated with conducting cell-based therapy research in rare pediatric rheumatic diseases and discuss future opportunities for innovation and development in this area.
Speaker: Georg Schett, MD – Friedrich-Alexander-Universität Erlangen-Nürnberg