John Stone, MD,MPH
Professor of Medicine; The Edward Fox Chair in Medicine
Massachusetts General Hospital , Harvard Medical School
Concord, Massachusetts, United States
Disclosure(s): Acepodia: Consultant (Ongoing); Alentis: Consultant (Ongoing); Alexion: Consultant (Ongoing)
Yoshiya Tanaka, MD, PhD
University of Occupational and Environmental Health, Japan
Kitakyushu, Japan
Disclosure(s): Otsuka: Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing)
Theresa Lu, MD, PhD
Hospital for Special Surgery
NEW YORK, New York, United States
Disclosure(s): Mestag Therapeutics: Advisor or Review Panel Member (Ongoing)
IgG4 is closely associated with tissue fibrosis in a condition called IgG4-related disease (IgG4-RD), where elevated levels of IgG4 antibodies are found alongside significant tissue inflammation and scarring (fibrosis) in various organs throughout the body. The disease pathogenesis remains poorly understood. In this session, the speakers will discuss how multi-omic approaches to immunophenotyping a large cohort of IgG4-related disease patients can be used to provide insight into the disease and how immunoglobulins can contribute to tissue fibrosis.
Speaker: Shingo Nakayamada, MD, PhD – University of Occupational and Environmental Health, Japan
Speaker: Shiv Pillai, MD, PhD – Harvard Medical School
