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Final Program


Schedule at a Glance
Legend
Program: Scientific Session
General Topic: Basic Science

From Omics to Action: Redefining the Immune Landscape in RA Joint

Monday, October 27, 2025
10:00 AM – 11:30 AM Central Time

    Moderator(s)

  • SD

    Samuel Dowling, MD, PhD

    Lurie Children's Hospital, Northwestern University
    Chicago, Illinois, United States

    Disclosure(s): No financial relationships with ineligible companies to disclose

  • Deepak Rao, MD, PhD

    Brigham and Women's Hospital
    Boston, Massachusetts, United States

    Disclosure(s): Aditum: Consultant (Ongoing); AstraZeneca: Consultant (Ongoing); Dragonfly: Advisor or Review Panel Member (Ongoing); Epana: Advisor or Review Panel Member (Ongoing); HiFiBio: Consultant (Ongoing); Janssen: Grant/Research Support (Terminated); Merck: Consultant (Ongoing)

    • Session Coordinator(s)

  • Carla Cuda, PhD

    Northwestern University
    Chicago, Illinois, United States

    Disclosure information not submitted.

This session is bringing new light to single-cell data by diving deeper into the function of nuanced cell subsets. A panel of experts will present functional data on myeloid, lymphoid, and stromal cells in rheumatoid arthritis (RA) and then discuss as a group the challenges that are present in this science and technology and future directions.

Learning Objectives:

  • Differentiate cellular subsets and their pathogenic roles in RA
  • Explain cellular crosstalk in the joint
  • Recognize the role of non-immune cells in RA pathogenesis

Presentations:

  • 10:00 AM – 10:30 AM Central Time
    Tissue-Resident, Extravascular Ly6c- Monocytes Are Critical for Inflammation in the Synovium

    Speaker: Harris Perlman, PhD – Northwestern University

  • 10:30 AM – 11:00 AM Central Time
    Fibroblast Zonation in Rheumatoid Arthritis

    Speaker: Kevin Wei, MD, PhD – Brigham and Women's Hospital at Harvard Medical School

  • 11:00 AM – 11:30 AM Central Time
    RA Synovial Cell Types and Spatial Niches Involved in Pannus Formation

    Speaker: Laura Donlin, PhD – Hospital for Special Surgery