Richard Loeser, Jr, MD, MACR
University of North Carolina
Chapel Hill, North Carolina, United States
Disclosure(s): LadeRx: Grant/Research Support (Ongoing); Novartis: Consultant (Ongoing); Regenosine: Grant/Research Support (Ongoing), Officer or Board Member (Ongoing)
Baohong Zhao, MD, PhD
Hospital for Special Surgery
New York, New York, United States
Disclosure information not submitted.
Baohong Zhao, MD, PhD
Hospital for Special Surgery
New York, New York, United States
Disclosure information not submitted.
Osteoarthritis (OA) affects the entire joint, causing damage to multiple cell types and resulting in pain. At present, there are no methods that effectively address both joint degeneration and pain reduction simultaneously. The drivers of OA are largely unknown. This session will highlight mostly recent groundbreaking findings in OA pathogenesis and potential promising therapeutic targets. Dr. Siddhartha Mukherjee will discuss how a Grem1-lineage chondrogenic progenitor causes OA. Dr. Matt Greenblatt will discuss how skeletal stem cells contribute to bone and cartilage regeneration.
Speaker: Dongsu Park, PhD – Baylor College of Medicine
Speaker: Matthew Greenblatt, MD, PhD – Weill Cornell
