Tissue Is the Issue: How Kidney Physiology Impacts Immunity

Tuesday, October 28, 2025

1:00 PM – 2:00 PM Central Time

Moderator(s)

TL

Theresa Lu, MD, PhD

Hospital for Special Surgery
NEW YORK, New York, United States

Disclosure(s): Mestag Therapeutics: Advisor or Review Panel Member (Ongoing)
JT

Jeremy Tilstra, MD, PhD

University of Pittsburgh
Pittsburgh, Pennsylvania, United States

Disclosure(s): Souffle theraputics: Consultant (Ongoing)

Session Coordinator(s)

JT

Jeremy Tilstra, MD, PhD

University of Pittsburgh
Pittsburgh, Pennsylvania, United States

Disclosure(s): Souffle theraputics: Consultant (Ongoing)

This session discusses how dysfunction of renal vascular development and immunity contributes to kidney injury and disease. Dr. Susan Quaggin discusses how abnormal blood and lymphatic vascular signaling leads to renal dysfunction. Dr. Joe Craft discusses how T-cell function regulates their ability to traffic to the kidneys in lupus nephritis.

Learning Objectives:

Describe the role of the blood vasculature in renal physiology
Describe the consequences of abnormal lymphatic development to renal function
Describe how T-cell functional phenotype is linked to T-cell trafficking to the kidney in lupus

Presentations:

1:00 PM – 1:30 PM Central Time

Glomerular Defects Drive Kidney Disease
1:30 PM – 2:00 PM Central Time

Trafficking of Immune Cells into the Kidney in SLE
Speaker: Joe Craft, MD – Yale University